Cancer Videos

New Treatments, Trials, and Cures

*Using the immune system*, Cancer vaccine shows promising results - CNN

An experimental treatment for cancer patients uses a vaccine made from a patient’s own tumor. CNN's Sanjay Gupta reports.

- the approach that we take is that we actually do the surgery, we take the tumor out, and then we make the vaccine directly from that individual patient tumor, and then give that vaccine back to the patient.
- the vaccine triggers the body's immune system to attack multiple spots on the tumor cells.

Cancer vaccine shows promising results
An experimental treatment for cancer patients uses a vaccine made from a patient’s own tumor. CNN's Sanjay Gupta reports.

Dr Sanjay Gupta reports about a vaccine that attacks brain tumors - CNN

A vaccine may shift the odds against a common, deadly brain cancer. CNN's Dr. Sanjay Gupta reports.

Melanoma Treatment Huge Success in Early Study - ABC NEWS

Moffitt Cancer Center's Dr. Vernon Sondak comments on the personalized approach.
- until now we did not have the genetic markers, the bio signatures, of which melanoma should be treated one way and which should be treated another way.

New drug PLX4032 targets genetic mutation in 60% of people with melanoma, patients saw their tumor shrink - Nightly News

Doctors are experimenting with a promising new approach to treating an all-too-common and potentially deadly cancer.
- more than 80% saw their tumor shrink.
- PLX4032 targets a genetic mutation that appears in about 60% of people with melanoma.
- another drug called ipilimumab appears to cure 20%-30% of patients by stimulating the immune system.

New hope for melanoma patients

Nightly News
A new drug shows great promise in fighting melanoma.
- while the drug is affective the cancer often returned after a year sparking other research to combine other drugs.

Drug shrinks melanoma tumors

Emily Black, a melanoma patient describes her treatments, the side effects, and how surprised she was when her medication began to work.

Melanoma patient 'taking life one day at a time'

Epigenetics Lung Cancer Trial 30% of patients showed benefit; Epigenetic Therapies, changing a gene and how cancer cells acts - CBSNEWS

The money raised in 2008's Stand Up To Cancer campaign has already been put to work creating a dream team of doctors developing cutting-edge research in the fight against cancer. Dr. Jon LaPook reports on a revolutionary approach to fighting cancer called "Epigenetic Therapies."

- Epigenetic Therapies, Epigenome.
- Lung cancer for a patient had spread to liver and he signed up for experimental treatment at Johns Hopkins Kimmel Cancer Center that switches genes on/off .
- Epigenetic drugs do not try to kill the cancer cells, they try to change their behavior.
- Epigenetics Lung Cancer Trial 30% of patients showed benefit.

Cancer Fighting Dream Team
September 10, 2010 3:41 PM
The money raised in 2008's Stand Up To Cancer campaign has already been put to work creating a dream team of doctors developing cutting-edge research in the fight against cancer. Dr. Jon LaPook reports on a revolutionary approach to fighting cancer called "Epigenetic Therapies.";health

Preview: Stand Up To Cancer's Advanced Research
September 10, 2010 11:22 AM
Dr. Jon LaPook previews tonight's CBS Evening News special report on "Stand Up To Cancer" with a story on a new cutting edge research method that is providing hope for cancer patients.;health

Immunotherapy targets cancer cells with remarkable results
Cancer cells typically put up a chemical shield to protect against the bodyâ?Ts disease-fighting T cells. But immunotherapy can break down the shield and let the T cells get to work.

After Chemo, Kids Live With Side Effects - ABC NEWS

Dr. Howard Katzenstein of the Aflac Cancer Center and Emory U. comments.

- Chemo therapy kills growing cells as well as cancer cells.
- New targeted therapies target the cancer cells, what gene has gone wrong, what has gone wrong inside the cell, to leave normal cells inside the body unharmed.

Scottish Doctors Develop Cancer-Fighting Bandage - WSJ

Scottish doctors will today unveil a new high-tech device that they claim can tackle skin cancer with little pain and no scarring. Courtesy Sky News.

New cancer treatment uses a drug that trains white blood cells to more actively attack cancer cells - CNN

- The new FDA approved cancer treatment involves taking a patient's own white blood cells and using a drug that trains them to more actively attack cancer cells.
- "But the real breakthrough is the approval of this new way of treating disease, which could be used for other cancers and conditions, such as HIV"
- "It's a landmark in the sense that it would be the first approved cell-based immune therapy,"

'Landmark' cancer vaccine gets FDA approval

A combination of 2 antibody drugs shrank tumors in 40% of women with breast cancer whose tumors generate HER2 - Reuters

- T-DM1 -- an "armed antibody" that ties Roche Herceptin to a toxic chemotherapy compound from ImmunoGen.
- results shrank tumors in 9 of 23 women whose cancer had worsened after a median of 8 prior treatments.
- Herceptin is designed to block the function of HER2, a protein produced by a specific gene with cancer-causing potential, 25-30% of breast cancers.

Antibody combo shrinks breast cancer tumors-study

China scientists show how arsenic destroys deadly blood cancer by targeting and killing specific proteins that keep the cancer alive - Reuters

"Unlike chemotherapy, the side effects of arsenic (in treating acute promyelocytic leukemia) are very low. There is no hair loss or suppression of bone marrow (function). We are interested in finding out how arsenic can be used in other cancers,"
China scientists show how arsenic treats blood cancer
(Reuters) - Scientists in China have demonstrated how arsenic -- a favorite murder weapon in the Middle Ages -- destroys deadly blood cancer by targeting and killing specific proteins that keep the cancer alive.

New compound ASG-5ME uses a monoclonal antibody against target found in more than 90% of pancreatic cancer patients - EurekaAlert!

ASG-5ME is a potent, targeted compound designed to selectively kill cancer cells, -- "ASG-5ME is intended for pancreatic cancer patients who do not have a good prognosis with currently available therapies. We are very pleased to be able to offer this exciting agent in a clinical trial for patients with advanced pancreatic cancer,"

- The new investigational compound uses a monoclonal antibody against a target which is found in more than 90% of pancreatic cancer patients.
- The monoclonal antibody delivers a highly potent molecule called monomethyl auristatin E (MMAE) to selectively kill the pancreatic cancer cells.

New investigational compound targets pancreatic cancer cells

New cancer treatment uses characteristics built into DNA and RNA, and small RNA to activate self-destruct response - EurekAlert!

In the PNAS study, researchers demonstrated that this approach effectively eliminates lab-grown human brain, prostate and bone cancer cells in a mutation-specific manner.

- "The molecules are able to detect a mutation within a cancer cell, and then change conformation to activate a therapeutic response in the cancer cell, while remaining inactive in cells that lack the cancer mutation,"
- Here's how it works: Treatment involves two different small RNAS. The first small RNA will open up if --and only if-- it finds the cancer mutation. A positive "diagnosis" exposes a signal that was previously hidden within the small RNA. Once this small RNA is open, a second small RNA binds to it, setting off a chain reaction in which these RNA molecules continue to combine to form a longer chain. The length of the chain is an important part of the "treatment". Longer chains trick the cell into thinking it has been invaded by a virus, tripping a self-destruct response.

These cells will self-destruct in 5 ... 4 ...

New treatment activates death program in cancer cells

Scientists have developed quicker detection of biomarkers, a leap forward in early detection for Alzheimer's and cancer - EurekAlert! (article link)

- All diseases have proteins specifically linked to them called biomarkers.
- This would help doctors increase the success rate of treatment through early intervention and help drug companies develop more effective drugs for these diseases.

"This new strategy uses a probe to 'fish' for likely proteins, selecting them from a crowded blood sample," -- "A microgel on the probe works like a sponge, picking up proteins which have a charge or mass within a certain range." -- "You can do it in one day instead of a few days or even a week," -- "These types of probe would in theory be suitable for different classes of diseases, mainly Alzheimer's and the like, but I also hope they would have applications for cancer."

The Biotechnology Group want to develop biomarker detection techniques further, and are already working on a probe which can select one specific protein, rather than ranges of size or charge.

Scientists make leap forward in early detection for Alzheimer's and cancer
Scientists at the UK's National Physical Laboratory have developed a new strategy for quicker and more precise detection of biomarkers – proteins which indicate disease. The work could pave the way for new tools to detect early stages of Alzheimer's and cancer at the molecular level.

Can cancer patients benefit from new drug trials? - Reuters (article link)

(Reuters Health) - Patients with advanced head and neck cancer survived just as well on experimental drugs as they did on FDA-approved standard therapies in a new study.

- The findings suggest that doctors should consider referring their terminally ill patients to such trials.
- Patients survived an average of 12 weeks on FDA-approved treatments and 10.7 weeks on experimental drugs.
- 4 patients had some improvement in their cancer in response to the experimental drugs and 34 of them had no changes -- 1 patient died from a cause related to the treatment.

"There are worries about whether people who are vulnerable in this way are able to give informed consent" -- "you have to be very careful," -- "They've exhausted all the (treatments) that are available and standard," -- "there really isn't any better option for them. I think this is genuinely what many people want to do."

Can cancer patients benefit from new drug trials?

J&J widens access as cancer drug abiraterone acetate for advanced prostate cancer demonstrated an improvement in patient survival - Reuters (article link)

(Reuters) - All patients in a study of a Johnson & Johnson drug for advanced prostate cancer will be offered the medicine after an independent monitoring committee found it demonstrated an improvement in patient survival.

- A program to provide early access to abiraterone acetate for patients who meet specified medical criteria is being initiated,
- Patients in the study received either the J&J drug plus the steroid prednisone or a placebo plus prednisone.

Independent data monitoring committees routinely oversee clinical trials to look for signs of safety problems that would lead to a study being halted, or for evidence that a drug works so well that it would be unethical not to offer it to patients receiving other medicines.

J&J widens access as cancer drug helps survival

UK charity (CRT) to test experimental Astra cancer drug AZD-3965 that targets cell metabolism (MCT-1) - Reuters

(Reuters) - AstraZeneca has agreed a deal with the commercial arm of a British charity to take an experimental cancer drug into early clinical trials.
- The work will be carried out by the charity's development and commercialization arm, Cancer Research Technology (CRT).

AZD-3965, is one of a new class of cancer metabolism drugs and targets the monocarboxylate transporter 1 (MCT-1) which is essential in cell metabolism.
- The idea is that by blocking MCT-1 the drug could limit cancer cells' ability to generate energy, reducing their ability to survive.

AstraZeneca signed a previous agreement with CRT in February for a three-year alliance to work on projects aiming to exploit the fact cancer cells use energy differently to normal cells.

UK charity to test experimental Astra cancer drug

Prevention and Cancer

Risk-Reducing Surgery Helps Women Live Longer - ABC NEWS

The Dana-Farber Cancer Institute's Dr. Judy Garber comments on the study.
- Risk-Reducing surgeries, when should women consider having their ovaries removed for example.

Howcast Channel, How To Eat To Prevent Cancer - YouTube

You don't need supplements to prevent cancer — look to the food you eat every day to pack in all the healthy nutrients you need.

Study shows a diverse diet of fruits and vegetables may decrease the risk of lung cancer - CNN

- Fruits and vegetables cuts our risk of getting lung cancer.
- Those who eat a variety of fruits and vegetables decreased their chances of getting lung cancer.
- Results published in Cancer Epidemiology, Biomarkers & Prevention.

A new study shows a diverse diet of fruits and vegetables may decrease the risk of lung cancer. CNN's Patty Lane reports.
Veggies cut lung cancer risk?

Several tips on reducing cancer risk from toxins and pesticides - CNN

- To reduce exposure to pesticides Wash produce thoroughly.
- Some toxic substances that we eat, breathe or are exposed to daily can lead to cancer.
Environmental cancer risks

Food and Cancer

Mushrooms provide more selenium than any other fruit or vegetable, selenium believed to decrease some human cancers. - CBC News

“One of the most significant health benefits is the potential role played in inhibiting different types of cancer tumours,” says Hauck. “In fact, mushrooms provide more selenium than any other fruit or vegetable.” - Selenium contains a compound that is believed to decrease the incidence of some human cancers.
- They also contain anti-inflammatory compounds similar to those in over-the-counter painkillers.
- Source: Mushrooms Canada,

Mushrooms found to contain powerful health benefits, study shows

Women who reported taking at least 400 international units of vitamin D every day were at 24% lower risk of developing breast cancer - Reuters (article link)

- Breast cells have receptors for vitamin D raising the possibility that the nutrient could help regulate the division and proliferation of these cells;
- There's also growing evidence that vitamin D could help protect against other types of cancer.

Vitamin D in pill form may cut breast cancer risk

Brocoli may help beat any life-threatening disease like cancer and heart disease - Prevention (article link)

- Pick any life-threatening disease—cancer, heart disease, you name it—and eating more broccoli and its cruciferous cousins may help you beat it, Johns Hopkins research suggests.
- Averaging just four weekly servings of veggies like broccoli, cabbage, and cauliflower slashed the risk of dying from any disease by 26% among 6,100 people studied for 28 years. - linked to the amount of sulforaphane.

25 Ridiculously Healthy Foods

Garlic lowered ovarian, colorectal, and other cancer rates - Prevention (article link)

- Garlic contains heart-protecting compounds.
- Garlic contains more than 70 active phytochemicals, including allicin, which studies show may decrease high blood pressure by as much as 30 points.
- High consumption of garlic lowered rates of ovarian, colorectal, and other cancers, according to a research review in the American Journal of Clinical Nutrition.

25 Ridiculously Healthy Foods
The key to healthier garlic: Crush the cloves, and let them stand for up to 30 minutes before heating them, which activates and preserves the heart-protecting compounds, according to a 2007 study from Argentina

An ancient Chinese brew may help reduce the intestinal damage caused by chemotherapy - Reuters

PHY906 is the laboratory formulation of a 1,800-year-old Chinese formula containing peonies, a purple flower called skullcap, licorice and fruit from a buckthorn tree.
- "After a few days of treatment with PHY906, the medicine restored the damaged intestinal linings in the mice."
- "Irinotecan reduces tumor growth by itself but if you combine with PHY906, it will further reduce tumor growth,"
- "By itself, PHY906 does not decrease tumor growth, it has to be used in combination with chemotherapy."

According to the American Cancer Society, the economic impact from colorectal cancer in terms of premature death and disability is US$99 billion annually, excluding direct treatment costs.

Ancient brew may reduce gut damage after chemotherapy
(Reuters) - An ancient Chinese brew may help reduce the intestinal damage caused by chemotherapy given to colon and rectal cancer patients, researchers said on Thursday.

Study suggested a potential for scientists to develop curcumin as an anti-cancer drug to treat esophageal cancer - Reuters

Researchers at the Cork Cancer Research Center in Ireland treated esophageal cancer cells with curcumin -- a chemical found in the spice turmeric, which gives curries a distinctive yellow color -- and found it started to kill cancer cells within 24 hours.

- Previous scientific studies have suggested curcumin can suppress tumors.
- U.S. researchers said in 2007 they had found curcumin may help stimulate immune system cells in the Alzheimer's disease.
- McKenna said the study showed curcumin caused the cancer cells to die "using an unexpected system of cell messages."

"these cells showed no evidence of suicide, and the addition of a molecule that inhibits caspases and stops this "switch being flicked' made no difference to the number of cells that died, suggesting curcumin attacked the cancer cells using an alternative cell signaling system."

Scientists say curry compound kills cancer cells
(Reuters) - A molecule found in a curry ingredient can kill esophageal cancer cells in the laboratory, suggesting it might be developed as an anti-cancer treatment, scientists said on Wednesday.

Watercress compound (called phenylethyl isothiocyanate) may 'turn off' breast cancer signal - EurekaAlert!

As tumours develop they rapidly outgrow their existing blood supply so they send out signals which make surrounding normal tissues grow new blood vessels into the tumour which feed them oxygen and nutrients. The research shows that the plant compound (called phenylethyl isothiocyanate) found in watercress can block this process, by interfering with and 'turning off' in the function of a protein called Hypoxia Inducible Factor (HIF).

The research team was able to detect significant levels of the plant compound PEITC in the blood of the participants following the watercress meal, and most importantly, could show that the function of the protein HIF was also measurably affected in the blood cells of the women.

Watercress may 'turn off' breast cancer signal

Increased Risk of Cancer

Low-Carb, Animal-Based Diets, 14% increased risk in heart disease and 28% for cancer death - CNN

CNN's Elizabeth Cohen explains the benefits of eating a low-carbohydrate, plant-based diet.
Low-Carb, Animal-Based Diets
- 14% risk of heart disease death
- 28% risk of cancer death
CNN's Elizabeth Cohen explains the benefits of eating a low-carbohydrate, plant-based diet.

Positives of a plant-based diet

Tanning beds and cancer linked? 3,000 people a day are diagnosed with skin cancer – CNN

- 3,000 people a day are diagnosed with skin cancer.
- Over 1 million new cases and 11,600 deaths a year.
Lawmakers explore links surrounding indoor tanning and melanoma a day before the FDA reviews regulation of tanning beds.

CT scans linked to cancer - CNN

CNN's Dr. Sanjay Gupta talks about new studies indicating the radiation risk from CT scans is higher than thought.
- two new studies indicate that CT give off more radiation then previously thought
- 29,000 new cancer cases could be caused by scans according to study

Dr. Sanjay Gupta reports from Mossville, Louisiana, where residents say chemical plants are causing diseases - CNN

- Blood test revealed dioxin known carcinogens levels 3 times too high.
- Dioxin stored in fat, in pancreas leads to diabetes, in liver leads to cancer, in kidneys, and in the brain
Town says chemicals sicken
CNN's Dr. Sanjay Gupta reports from Mossville, Louisiana, where residents say chemical plants are causing diseases.

Cancer rates worry S.F. firefighters, toxins and dioxin - MSNBC

An alarming increase in reported cases of cancer has San Francisco firefighters concerned. KN TV's

Processed meat linked to an 18% higher risk of ovarian cancer, Omega-3 in fatty fish linked to 24% reduction in ovarian cancer risk - Reuters

- "Processed meat contains compounds that could damage cells and thereby cause cancer. Conversely, the omega-3 fatty acids found in fatty fish are thought to be good for health in many ways and may possess anti-cancer properties."
- Processed meats preserved with nitrites and nitrates can form nitrosamines, known causes of cancer in animals.
Processed meat linked to higher ovarian cancer risk
NEW YORK (Reuters Health) - Women who eat a lot of processed meats, such as salami and hot dogs, are at a higher risk of ovarian cancer, according to a new Australian study.

Obesity; Soda-cancer link? - CNN

A new study suggests a link between drinking soda and developing pancreatic cancer.
- A research study claims that there is an 87% increased risk of pancreatic cancer.
- linked to sugar
- obesity is linked to cancer

There was a relationship between increased pancreatic cancer risk and higher intakes of sugar, candy, honey and jam - Reuters (article links)

- Participants with the highest-glycemic index diets were 78% more likely to have pancreatic cancer.
- It is possible that such diets could contribute to pancreatic risk, such foods influence the body's secretion of the blood-sugar-regulating hormone insulin -- And insulin encourages the growth and division of cells in the pancreas -- raising the possibility that the hormone could encourage the growth and spread of pancreatic cancer cells.

Sugary foods linked to pancreatic cancer risk

NEW YORK (Reuters Health) - People with diets high in sweets and other foods that cause rapid blood-sugar spikes may have a higher risk of developing pancreatic cancer than those who eat less of those foods, a new study suggests.

Obesity accounts for 20% or more of cancer; A report that concludes Americans are under constant assault from carcinogenic agents - Reuters (article link)

One big problem -- people are soaked in chemicals, electromagnetic radiation, hormones and other known causes of cancer that can interact with thousands of genetic variations to start tumors growing -- or not. Figuring out whether any one ingredient is mutating a gene or set of genes in a certain way will be difficult.
- Tobacco use and other unhealthy behaviors cause cancer.
- Obesity; "The lack of physical activity, weight gain, obesity clearly account for 20% or more of cancer"
- Alcohol; "We know that alcohol causes 4% of cancers.

Cancer report energizes activists, not policy

Isolation and stress identified as contributing to breast cancer risk - EurekAlert

- The researchers found that isolation and stress result in a 3.3-fold increase in the risk of developing cancer among rats with naturally occurring mammary tumors.
- The researchers further found that rats living in isolation experienced a 135 percent increase in the number of tumors and a more than 8,000 percent increase in their size.
- The research establishes, for the first time, that isolation and stress could be a factor in human breast cancer risk

High radiation raises risk of second radiation-sensitive cancer such as breast, colon, lung, thyroid and bladder - Reuters

(Reuters) - Atomic bomb blast victims lucky enough to survive one cancer have a high risk of developing a second, U.S. researchers said on Wednesday, in a study that offers new insights about cancer risks from radiation exposure.

- "We found that radiation increases the risk of developing a second cancer in a very similar way to how it is related to risk of a first cancer," -- "We also found that cancer survivors had particularly high risks of developing a second cancer that we know to be radiation-sensitive. These include breast, colon, lung, thyroid and bladder cancers,"
- The findings would likely hold true for other types of radiation exposures known to cause cancer.

High radiation raises risk of second cancer: study

People and Cancer

Tennis great Martina Navratilova discusses her battle with breast cancer - CNN (video)

Tennis great Martina Navratilova discusses her battle with breast cancer and the decision to share her story.
Martina Navratilova's greatest battle

Considering genetic testing? It's not for everyone
Actress Angelina Jolie made headlines Tuesday when she announced in a New York Times op-ed that she had underwent a double mastectomy after finding out she had an 87 percent chance of getting breast cancer due to the BRCA1 gene. NBC's Dr. Nancy Snyderman reports.

CNN archives: Jolie on her mom's cancer

Jolie: 'I've decided to be proactive'

TV host: Why I had a double mastectomy

CNN anchor: I have breast cancer

Mammograms save lives

ESPN Digger Phelps recommends 2 prostate cancer screenings a year, may have saved him - Morning Joe

The ESPN college basketball analyst joins the Morning Joe gang to discuss the importance of early screening for prostate cancer.
- September is prostate cancer awareness month.
- Prostate cancer kills about 240, 000 men each year.
- Digger Phelps says go for a checkup twice a year, it may have saved him.
- Digger Phelps recommends going for a colonoscopy, prostate cancer screening, and physical at age 45.
Digger Phelps on truth about prostate cancer

Michael Douglas, the voice at top of Nightly News, has stage 4 throat cancer - Nightly News

People Magazine reports that actor Michael Douglas suffered from a sore throat and other symptoms of months before doctors discovered a throat tumor three weeks ago, but now he's in treatment and hopeful for a recovery.
- The voice of Michael Douglas at the top of Nightly News each night.
- He found out 3 weeks ago, Battling stage 4 throat cancer.
- Head and neck cancers, 30 thousand a year, he smoked cigarettes and drank.
- Stage 4 means the cancer has spread to the local lymph nodes.

Michael Douglas tackles new role as cancer patient

95% of Pancreatic cancer patients like Michael Landon, Patrick Swayze, and YouTube founder Randy Pausch die within 5 years - CNN

- Michael Landon, Patrick Swayze, and YouTube founder Randy Pausch
- 95% Pancreatic cancer patients die within 5 years of diagnosis, only 2% of federal cancer funds.
- "We cannot change the cards we are dealt, just how we play the hand" - Randy Pausch YouTube founder

Cancer support group: We need more cash
A group of advocates is lobbying for more pancreatic cancer research funding. CNN's Brianna Keilar reports.

Psilocybin in Cancer Research - ABC NEWS

Pam Sakuda was a cancer patient whose doctors prescribed psychedelic drugs.

100's of first responders have died post 911 from various cancers, no proof toxins from ground zero are to blame - CNN

CNN's Deborah Feyerick has the story of a 9/11 first responder who's fighting for his life.

- A rare blood cancer called mulitple Myeloma.
- 100's of first responders have died post 911 from various cancers there's no proof toxins from ground zero are to blame.
- Doctors say most cancers take longer than 9 years to develop.
CNN's Deborah Feyerick has the story of a 9/11 first responder who's fighting for his life.

Rare cancer threatens 9/11 worker

CNN's Elizabeth Cohen talks to a 9/11 first responder who blames his cancer on the grueling work at ground zero.

9/11 responder blames cancer on attack